In patients with end-stage chronic liver diseases, esophageal varices can be a life-threatening complication of portal hypertension because of bleeding risk. In this study, we explored the role of MR elastography (MRE) in stratifying portal hypertension severity and predicting high-risk varices by using upper gastrointestinal endoscopy as the reference standard. We concluded that a composite model including spleen size and stiffness plus liver stiffness and platelet count more accurately predicts the presence of high-risk varices, and thus could reduce unnecessary endoscopies more precisely than using liver stiffness and platelet count alone.
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