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Abstract #0313

High-risk Esophageal Varices Screening with MR Elastography in Patients with Cirrhosis

Safa Hoodeshenas1, Mahmoud Adam Tahboub Amawi2, Jingbiao Chen1,3, Nimish Thakral2, Kevin J. Glaser1, Bogdan Dzyubak1, Jiahui Li1, Xin Lu1, Jie Chen1, Zheng Zhu1, Patrick S. Kamath2, Vijay Shah2, Richard L. Ehman1, Sudhakar K. Venkatesh1, Douglas A. Simonetto2, and Meng Yin1
1Department of Radiology, Mayo Clinic, Rochester, MN, United States, 2Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, United States, 3The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

In patients with end-stage chronic liver diseases, esophageal varices can be a life-threatening complication of portal hypertension because of bleeding risk. In this study, we explored the role of MR elastography (MRE) in stratifying portal hypertension severity and predicting high-risk varices by using upper gastrointestinal endoscopy as the reference standard. We concluded that a composite model including spleen size and stiffness plus liver stiffness and platelet count more accurately predicts the presence of high-risk varices, and thus could reduce unnecessary endoscopies more precisely than using liver stiffness and platelet count alone.

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