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Abstract #0407

Going Below The Neck:  Physiological limits on use of 300 mT/m gradients in the human body

Malwina Molendowska1, Fabrizio Fasano2,3, Umesh Rudrapatna1, Ralph Kimmlingen3, Derek K. Jones1,4, Slawomir Kusmia1, Chantal M. W. Tax1,5, and C. John Evans1
1Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, United Kingdom, 2Siemens Healthcare Ltd, Camberly, United Kingdom, 3Siemens Healthcare GmbH, Erlangen, Germany, 4Mary McKillop Institute for Health Research, Faculty of Health Sciences, Australian Catholic University, Melbourne, Australia, 5Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands

Increasing-available ultra-strong gradient systems introduce a new challenge in MRI: the unknown interaction of time-varying magnetic fields with the human body. We characterise the physiological effects of deploying 300 mT/m gradients Siemens Connectom system when imaging regions below the neck (i.e., heart and prostate). We show gradient amplitude thresholds for PNS (ramp times < 2ms) are first reached on the Y-gradient. Moreover, landmarking on the heart gives the highest probability of generating magnetophosphenes (all gradient-axes). This study establishes: (i) limitations in greatest system performance; and (ii) that the so-far head-only Connectom system can be safely used in ‘below-the-neck’ applications.

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