3D Cartesian turbo spin echo (TSE) is a promising acquisition method for renal ASL because of its improved SNR and compatibility with optimal background suppression (BGS). However, 3D Cartesian TSE with single average can limit its SNR and robustness. In this study, we applied a variable density sampling approach to renal ASL imaging, which acquires the center of the k-space with higher signal averages and improves SNR and robustness without significantly prolonging scan time. We combined this with partial k-space acquired M0 images to compensate for increased scan time, but without compromising perfusion quantification.
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