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Abstract #0442

A regularized joint water/fat separation and B0 map estimation for 2D-navigated interleaved EPI based diffusion MRI

Yiming Dong1, Kirsten Koolstra2, Malte Riedel3, Matthias J.P. van Osch1, and Peter Börnert1,4
1C.J. Gorter Center for High Field MRI, Department of Radiology, LUMC, Leiden, Netherlands, 2Division of Image Processing, Department of Radiology, LUMC, Leiden, Netherlands, 3University of Lübeck, Lübeck, Germany, 4Philips Research Hamburg, Hamburg, Germany

Multi-shot EPI enables high-resolution diffusion-weighted imaging with reduced geometric distortions. However, fat is often a confounding factor in EPI, especially in regions with severe B0 inhomogeneities. For the proposed method, data is acquired using TE-shifted interleaved EPI and 2D-navigators to sense the motion-induced shot phases. The reconstruction includes a multi-peak fat model and corrects for the fat frequency-specific chemical shift displacements in phase-encoding direction by a time-efficient image-space formulation. In-vivo results show that the proposed algorithm provides improved water/fat separation compared with the conventional technique and fat-suppressed acquisition.

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