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Abstract #0458

Extreme Looping Star: Quiet fMRI at high spatiotemporal resolution

Andrew Palmera Leynes1,2, Nikou Louise Damestani3, David John Lythgoe3, Ana Beatriz Solana4, Brice Fernandez5, Brian Burns1,6, Steven Charles Rees Williams3, Fernando Zelaya3, Peder E.Z. Larson1,2, and Florian Wiesinger3,4
1Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States, 2UC Berkeley - UC San Francisco Joint Graduate Program in Bioengineering, Berkeley and San Francisco, CA, United States, 3King's College London, London, United Kingdom, 4GE Healthcare, Munich, Germany, 5GE Healthcare, Paris, France, 6GE Healthcare, Menlo Park, CA, United States

The Looping Star pulse sequence was recently introduced as an acoustically silent alternative to EPI-based fMRI pulse sequences. In this abstract, we present improvements to the spatiotemporal resolution of Looping Star using the “extreme MRI” approach, without sacrificing functional sensitivity. We demonstrate the application of silent fMRI with increased temporal resolution and increased spatial resolution using extreme Looping Star, in comparison with standard Looping Star, on a motor task and a visual task across two sites.

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