Abstract #0458

Extreme Looping Star: Quiet fMRI at high spatiotemporal resolution

Andrew Palmera Leynes^1,2, Nikou Louise Damestani³, David John Lythgoe³, Ana Beatriz Solana⁴, Brice Fernandez⁵, Brian Burns^1,6, Steven Charles Rees Williams³, Fernando Zelaya³, Peder E.Z. Larson^1,2, and Florian Wiesinger^3,4

¹Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States, ²UC Berkeley - UC San Francisco Joint Graduate Program in Bioengineering, Berkeley and San Francisco, CA, United States, ³King's College London, London, United Kingdom, ⁴GE Healthcare, Munich, Germany, ⁵GE Healthcare, Paris, France, ⁶GE Healthcare, Menlo Park, CA, United States

The Looping Star pulse sequence was recently introduced as an acoustically silent alternative to EPI-based fMRI pulse sequences. In this abstract, we present improvements to the spatiotemporal resolution of Looping Star using the “extreme MRI” approach, without sacrificing functional sensitivity. We demonstrate the application of silent fMRI with increased temporal resolution and increased spatial resolution using extreme Looping Star, in comparison with standard Looping Star, on a motor task and a visual task across two sites.

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