Abstract #0480

Comparison of Quantitative 3D Magnetic Resonance Cholangiopancreatography Biliary Tree Metrics derived from 3 Different Acquisition Methods

Neeraja Mahalingam¹, George Ralli², Gerard Ridgway², Andrew Trout^3,4,5, and Jonathan Dillman^3,4,6

¹Imaging Research Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States, ²Perspectum Ltd., Oxford, United Kingdom, ³Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States, ⁴Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, United States, ⁵Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States, ⁶Center for Autoimmune Liver Disease, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States

Comparison of the performance of different methods of acquiring three-dimensional (3D) magnetic resonance cholangiopancreatography (MRCP) data have been largely qualitative. MRCP+ prototype software (Perspectum Ltd.; Oxford, UK) was used to derive quantitative biliary tree metrics from 3D MRCP acquired using three different methods. Intra-class correlation coefficients (ICCs) demonstrated strong agreement on biliary tree volume, median intrahepatic duct diameters, number of ducts, and length of dilations between 3D FSE and CS-FSE MRCP (ICCs=0.84-0.93); there was slightly less agreement between CS-FSE and 3D GRASE MRCP. Our results suggest that CS-FSE provides comparable visualization of the biliary system to conventional 3D FSE MRCP.

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