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Abstract #0481

Investigation of risk factors for pancreatic exocrine insufficiency using 3T multiparametric MR imaging

Hidemitsu Sotozono1, Akihiko Kanki1, Kazuya Yasokawa1, Akira Yamamoto1, Tsutomu Tamada1, and Yu Ueda2
1Radiology, Kawasaki Medical School, Kurashiki, Japan, 2Philips Japan, Tokyo, Japan

Retrospective study included 46 patients without pancreatic disorders including pancreatic tumor and acute pancreatitis who underwent 3T abdominal multi-parametric MRI including cine-dynamic with spatially selective inversion recovery pulse and proton density fat fraction in 3D mDIXON quant (PDFF (%)). Pancreatic exocrine function was assessed as secretion grade (SG) based on the travel distance of inflowing pancreatic juice in the main pancreatic duct on cine-dynamic MRCP. The negative correlation between PDFF of the pancreas and SG estimated by cine-dynamic MRCP with spatially selective IR pulse suggests an association between pancreatic steatosis and impaired pancreatic exocrine function.

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