Abstract #0515

A rapid in vivo method for mapping cortical connections of primate amygdala with infrared neural stimulation and 7T fMRI

Augix Guohua Xu¹, Sunhang Shi¹, Yunyun Rui¹, Xiaotong Zhang¹, Lizabeth Romanski², Katalin M. Gothard³, and Anna Wang Roe¹

¹Interdisciplinary Institute of Neuroscience and Technology, Zhejiang University, Hangzhou, China, ²Dept of Neuroscience, University of Rochester School of Medicine, Rochester, NY, United States, ³University of Arizona, Dept of Physiology, Tucson, AZ, United States

We have previously shown that INS-fMRI is a rapid method for mapping mesoscale brain networks in the macaque monkey brain. Here, we extend this capability by stimulating deep brain sites. We test this new method by stimulating the basal nucleus of amygdala in the macaque monkey. The connections we identified are consistent with dye-tracing studies. In conclusion, our results indicate that INS-fMRI is a promising novel method for mapping connections of deep brain structures at high spatial resolution.

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