A unique approach to analysis of wrist mechanics is analyzed. In this approach, 4D dynamic MRI is utilized to track unconstrained movement of individual wrist carpal bones. Through a boundary-based slab-to-volume registration approach, fiducial points identified or computed on high resolution static images are tracked using the dynamic time series to generate time-domain signals indicative of independent and relative carpal bone movement. After rudimentary processing of 12 derived signals, each computed on 3 asymptomatic control subjects, correlation analysis is utilized to elucidate the utility of these metrics in establishing a normative kinematic profile of the healthy wrist.
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