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Abstract #0523

Assessing the Viability of Carpal Bone Kinematic Profiles Extracted from 4D MRI

Kevin Matthew Koch1, Mohammad Zarenia2, V. Emre Arpinar2, L Tugan Muftuler3, Alyssa Joy Schnorenberg 4, Joshua Leonardis4, Brooke Slavens4, and Andrew S Nencka2
1Medical College of Wisconsin, Milwaukee, WI, United States, 2Radiology, Medical College of Wisconsin, Milwaukee, WI, United States, 3Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States, 4University of Wisconsin, Milwaukee, Milwaukee, WI, United States

A unique approach to analysis of wrist mechanics is analyzed. In this approach, 4D dynamic MRI is utilized to track unconstrained movement of individual wrist carpal bones. Through a boundary-based slab-to-volume registration approach, fiducial points identified or computed on high resolution static images are tracked using the dynamic time series to generate time-domain signals indicative of independent and relative carpal bone movement. After rudimentary processing of 12 derived signals, each computed on 3 asymptomatic control subjects, correlation analysis is utilized to elucidate the utility of these metrics in establishing a normative kinematic profile of the healthy wrist.

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