Given the prevalence and disease burden of osteoporosis, it is critical to detect it as early as possible. This is challenging not only because the disease is typically asymptomatic but also due to known limitations of the gold standard method of DEXA. The aim of this study was to determine if alternative approach of 2D texture analysis in L1-L5 lumbar spine on T1W images can be used to detect osteoporosis. It is demonstrated that such an approach can indeed be used to clinically detect osteoporosis with an AUC of 0.8.
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