Abstract #0525

Transverse Relaxation Anisotropy of Tendons Studied by MR Microscopy

Benedikt Hager^1,2,3, Markus M. Schreiner⁴, Sonja M. Walzer⁴, Lena Hirtler⁵, Vladimir Mlynarik¹, Martin Zalaudek¹, Andreas Berg⁶, Xeni Deligianni^7,8, Oliver Bieri^7,8, Reinhard Windhager⁴, Vladimir Juras¹, and Siegfried Trattnig¹

¹Department of Biomedical Imaging and Image-guided Therapy, High Field MR Centre, Medical University of Vienna, Vienna, Austria, ²CD Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, ³Austrian Cluster for Tissue Regeneration, Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria, ⁴Department of Orthopedics and Trauma-Surgery, Medical University of Vienna, Vienna, Austria, ⁵Center for Anatomy and Cell Biology, Division of Anatomy, Medical University of Vienna, Vienna, Austria, ⁶Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria, ⁷Division of Radiological Physics, Department of Radiology, University of Basel Hospital, Basel, Switzerland, ⁸Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland

In this study, we analyzed the T₂* anisotropy and mono- vs. bi-exponentiality of T₂* decay of Achilles and patellar tendons in vitro with a variable echo time sequence, ultrashort echo times and microscopic resolution and compared the results with histological findings. A total of four human Achilles tendons and four patellar tendons were measured at their maximum and minimum dipolar interaction (0°, 55°). In addition, one Achilles tendon and one patellar tendon were measured at 11 fiber-to-field angles (0,10,20,30,40,50,60,70,80,90°) each in order to study the change in T₂* values at these angles.

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