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Abstract #0550

Simultaneous 3D T1 and B1+ mapping at 7T using MPRAGE with multiple volumes and driven equilibrium (DE)

Hampus Olsson1, Mads Andersen2, Mustafa Kadhim1, and Gunther Helms1
1Department of Medical Radiation Physics, Clinical Sciences Lund, Lund University, Lund, Sweden, 2Philips Healthcare, Copenhagen, Denmark

MP2RAGE has become popular for T1 mapping at 7T. Accuracy is yet improved by using a separately acquired flip angle map when creating the protocol-specific lookup table. Here, two additional volumes acquired at differing flip angles are added to an MP2RAGE sequence to obtain two separate states of driven equilibriums, effectively forming a dual flip angle protocol within the cycle. By estimating the accelerated effective relaxation, T1*, from the signals, both T1 and B1+ can be solved for analytically. Thus, a multi-volume MPRAGE sequence is turned into a dedicated high-resolution T1 and flip angle-mapping protocol.

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