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Abstract #0552

Motion-Resolved Brain MRI for Quantitative Multiparametric Mapping

Sen Ma1, Nan Wang1, Zhaoyang Fan1, Yibin Xie1, Debiao Li1, and Anthony G. Christodoulou1
1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States

We introduce a motion-resolved solution to clinical brain MRI for quantitative multiparametric mapping using Multitasking. We demonstrate that the proposed approach is generalizable to translation, rotation, discrete motion, and periodic motion without explicit need for motion correction or compensation. Both simulation and in vivo results show that the proposed motion-resolved approach produces better image quality with sharp tissue structure and without ghosting/blurring artifacts, which outperforms no motion handling and simple motion removal. The motion-resolved approach yields substantially less RMSE in terms of quantitative mapping accuracy compared to no motion handling and simple motion removal.

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