Abstract #0581

4D Phase Contrast MRI detects heterogeneous strain rate patterns along the length of the Tibialis Anterior muscle during dynamic contractions

Thom T. J. Veeger¹, Gustav J. Strijkers², Valentina Mazzoli³, Hans C. van Assen¹, Jurriaan H. de Groot⁴, Lukas M. Gottwald⁵, Aart J. Nederveen⁵, Hermien E. Kan^1,6, and Melissa T. Hooijmans²

¹Radiology, Leiden University Medical Center, Leiden, Netherlands, ²Biomedical Engineering & Physics, Amsterdam Movement Sciences, Amsterdam University Medical Center, Location AMC, Amsterdam, Netherlands, ³Radiology, Stanford University, Stanford, CA, United States, ⁴Rehabilitation Medicine, Leiden University Medical Center, Leiden, Netherlands, ⁵Radiology and Nuclear Medicine, Amsterdam Movement Sciences, Amsterdam University Medical Center, Location AMC, Amsterdam, Netherlands, ⁶Duchenne Center Netherlands, Veenendaal, Netherlands

We assessed strain rate distributions within the Tibialis Anterior muscle by acquiring whole lower leg 4D PC-MRI during dynamic exercise, with and without load. Our data revealed a spatially heterogeneous strain rate pattern along the length of the Tibialis Anterior muscle during movement cycle. During dorsiflexion, the smallest negative strain rates were observed (in first approximation) along the fiber in the most proximal segment and the largest positive strain rates (in first approximation) across the fiber in the most distal segment, while plantarflexion showed the expected opposite. No effect of load was detected on strain rates.

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