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Abstract #0584

Spontaneous Muscular Activities and Estimating their Influence on Derived Diffusion Tensor Parameters

Martin Schwartz1,2, Petros Martirosian1, G√ľnter Steidle1, Bin Yang2, and Fritz Schick1
1Section on Experimental Radiology, University Hospital of Tuebingen, Tuebingen, Germany, 2Institute of Signal Processing and System Theory, University of Stuttgart, Stuttgart, Germany

Estimation of diffusion tensor parameters in healthy subjects and patients suffering from neuromuscular disease can be markedly affected by a high rate of spontaneous muscular activities during the MR examination. Therefore, a concept for realistic simulation of spontaneous muscular activities in diffusion tensor imaging and the estimation of their influence on derived parameters is given in this work. The degradation of the derived parameters depends strongly on the robustness of the chosen approach for tensor estimation.

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