Abstract #0597

Intensity Based Visualization of Pulmonary Function Using Time to Peak and Full Width at Half Max Biomarkers on Ultrashort Echo Time (UTE) MRI

Darren Hsu¹, Fei Tan², Michael Lustig³, and Peder E. Z. Larson⁴

¹Department of Computer Science, University of California, Berkeley, Berkeley, CA, United States, ²Department of Bioengineering, University of California, Berkeley - University of California, San Francisco, San Francisco, CA, United States, ³Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, United States, ⁴Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States

The visualization of respiratory inhalation-exhalation cycles are applied to pulmonary MR images. Using 3D UTE phase resolved MR Images, respiratory phases were reconstructed from free breathing images. Applying signal intensity based methods, biomarker metrics such as time to signal intensity peak (TTP) or full width at half maximum (FWHM) intensity are extracted from the image. The resulting visualizations depict localized respiratory function to help clinicians understand the rate and velocity at which lung tissue expands from full inspiration to full expiration.

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