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Abstract #0598

CEST Imaging vs. Diffusion-Weighted Imaging vs. FDG-PET/CT vs. Combined Method: Prediction Capability for Recurrence in NSCLC Patients

Yoshiharu Ohno1,2,3, Masao Yui4, Takeshi Yoshikawa3,5, Yoshimori Kassai4, Kaori Yamamoto4, Kazuhiro Murayama2, and Hiroshi Toyama1
1Radiology, Fujita Health University School of Medicine, Toyoake, Japan, 2Joint Research Laboratory of Advanced Medical Imaging, Fujita Health University School of Medicine, Toyoake, Japan, 3Division of Functional and Diagnostic Imaging Research, Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan, 4Canon Medical Systems Corporation, Otawara, Japan, 5Diagnostic Radiology, Hyogo Cancer Center, Akashi, Japan

No major reports have been reported the comparison of capability for differentiating recurrence from non-recurrence groups in candidates for surgical resection due to lung cancer among CEST imaging, DWI and PET/CT. We hypothesized that CEST imaging, which was determined as APT-weighted (APTw) imaging at 3.5 ppm, had equal or better potential for prediction of postoperative recurrence prediction in postoperative lung cancer patients, when compared with DWI and FDG-PET/CT. The purpose of this study was to compare the prediction capability of among single- and multi-parametric approaches by APTw imaging, DWI, and FDG-PET/CT in NSCLC patients.

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Abstract