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Abstract #0615

3D whole-heart free-breathing isotropic joint T1/T2 quantification: preliminary clinical evaluation

Carlos Velasco1, Giorgia Milotta1, Alina Hua1, Karl Kunze1,2, Radhouene Neji1,2, Tevfik Ismail1, Claudia Prieto1, and René M. Botnar1
1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom

Myocardial tissue characterization, such as quantification of fibrosis and oedema plays an important role in many myocardial diseases. T1 and T2 maps are typically acquired sequentially in 2D under several breath-holds. However, they achieve limited spatial resolution and coverage. To overcome these limitations, a high resolution, motion compensated joint T1/T2 water/fat sequence has been recently proposed and validated in phantom and healthy subjects. In this study, we demonstrate the capability of the proposed approach to obtain whole-heart, motion-compensated, simultaneous and co-registered T1, T2 maps and water and fat images in ~9min in patients with cardiovascular disease.

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