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Abstract #0691

Simultaneous T1, T2 and T1Ρ cardiac Magnetic Resonance Fingerprinting for Contrast-free Myocardial Tissue Characterization

Carlos Velasco1, Gastao Cruz1, René M. Botnar1, and Claudia Prieto1
1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

Cardiac Magnetic Resonance Fingerprinting (MRF) has shown promising results for myocardial fibrosis and inflammation characterization. In addition, T mapping has shown promising results for detection of focal and diffuse myocardial fibrosis without the need of exogenous contrast agents. However, multiparametric T1, T2 and T mapping requires sequential acquisitions under several breath-holds, that can lead to non-registered maps and bias due to inter-parameter dependencies. In this work we propose a cardiac MRF acquisition scheme for simultaneous quantification of myocardial T1, T2 and T in a contrast-free single breath-hold MR scan. The proposed approach has been investigated in phantoms and healthy subjects.

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