Abstract #0690

3D Whole-ventricle, Free-Breathing, Non-ECG, T1-T2-B1+ Mapping and Cine Imaging with Cardiac MR Multitasking

Xianglun Mao¹, Fardad M Serry¹, Sen Ma¹, Zhehao Hu^1,2, Alan C Kwan^1,3, Fei Han⁴, Yibin Xie¹, Debiao Li^1,2, and Anthony G Christodoulou^1,2

¹Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ²Department of Bioengineering, University of California in Los Angeles, Los Angeles, CA, United States, ³Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ⁴Siemens Medical Solutions Inc., Los Angeles, CA, United States

Conventional cardiovascular MR (CMR) exams are relatively inefficient and demanding for patients because 1) they rely on methods that necessitate breath-holding or intermittent pauses (via gating) to compensate for motion, 2) images are acquired as a series of 2D slices often with large gaps. We propose a single 3D free-breathing acquisition without ECG requirements, providing motion resolved, quantitative T1 and T2 cine mapping with whole-ventricle coverage with high resolution and no slice gaps. The 3D Multitasking framework additionally incorporates a B1+ component, critical for accurate T1 measurement at 3T. This technique is preliminarily validated both in phantoms and healthy volunteers.

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