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Abstract #0690

3D Whole-ventricle, Free-Breathing, Non-ECG, T1-T2-B1+ Mapping and Cine Imaging with Cardiac MR Multitasking

Xianglun Mao1, Fardad M Serry1, Sen Ma1, Zhehao Hu1,2, Alan C Kwan1,3, Fei Han4, Yibin Xie1, Debiao Li1,2, and Anthony G Christodoulou1,2
1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2Department of Bioengineering, University of California in Los Angeles, Los Angeles, CA, United States, 3Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 4Siemens Medical Solutions Inc., Los Angeles, CA, United States

Conventional cardiovascular MR (CMR) exams are relatively inefficient and demanding for patients because 1) they rely on methods that necessitate breath-holding or intermittent pauses (via gating) to compensate for motion, 2) images are acquired as a series of 2D slices often with large gaps. We propose a single 3D free-breathing acquisition without ECG requirements, providing motion resolved, quantitative T1 and T2 cine mapping with whole-ventricle coverage with high resolution and no slice gaps. The 3D Multitasking framework additionally incorporates a B1+ component, critical for accurate T1 measurement at 3T. This technique is preliminarily validated both in phantoms and healthy volunteers.

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