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Abstract #0755

Whole-Heart Motion-Resolved Multi-Peak Fat-Fraction Mapping using Free-Running 3D Radial Multi-Echo GRE and Pilot Tone

Adèle L. C. Mackowiak1, Christopher W. Roy1, Jérôme Yerly1,2, Lorenzo Di Sopra1, Mariana B. L. Falcaõ1, Mario Bacher1,3, Peter Speier3, Davide Piccini4,5, Matthias Stuber1,2, and Jessica A. M. Bastiaansen1
1Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 2CIBM Center for Biomedical Imaging, Lausanne, Switzerland, 3Siemens Healthcare GmbH, Erlangen, Germany, 4Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 5Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland

A free-running multi-echo GRE approach was proposed for whole-heart fat quantification. Retrospective extraction of cardiac and respiratory motion states was achieved using integrated Pilot Tone navigation, enabling a free-breathing non-ECG-triggered acquisition. Following a motion-resolved compressed sensing based image reconstruction of the separate echoes, fat fraction, water fraction, R2* and B0 maps, as well as separated fat and water images, were calculated. Free-running acquisition parameters were optimized in a fat phantom. Volunteer experiments demonstrated the feasibility of motion-resolved free-running fat-fraction mapping technique in a 6-minute scan time.

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