Abstract #0755

Whole-Heart Motion-Resolved Multi-Peak Fat-Fraction Mapping using Free-Running 3D Radial Multi-Echo GRE and Pilot Tone

Adèle L. C. Mackowiak¹, Christopher W. Roy¹, Jérôme Yerly^1,2, Lorenzo Di Sopra¹, Mariana B. L. Falcaõ¹, Mario Bacher^1,3, Peter Speier³, Davide Piccini^4,5, Matthias Stuber^1,2, and Jessica A. M. Bastiaansen¹

¹Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ²CIBM Center for Biomedical Imaging, Lausanne, Switzerland, ³Siemens Healthcare GmbH, Erlangen, Germany, ⁴Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ⁵Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland

A free-running multi-echo GRE approach was proposed for whole-heart fat quantification. Retrospective extraction of cardiac and respiratory motion states was achieved using integrated Pilot Tone navigation, enabling a free-breathing non-ECG-triggered acquisition. Following a motion-resolved compressed sensing based image reconstruction of the separate echoes, fat fraction, water fraction, R₂* and B₀maps, as well as separated fat and water images, were calculated. Free-running acquisition parameters were optimized in a fat phantom. Volunteer experiments demonstrated the feasibility of motion-resolved free-running fat-fraction mapping technique in a 6-minute scan time.

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