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Abstract #0787

Submillimeter, Sub-Minute Quantitative Susceptibility Mapping using a Multi-Shot 3D-EPI with 2D CAIPIRINHA Acceleration

Monique Tourell1,2, Jin Jin2,3, Ashley Stewart1,2, Saskia Bollmann1, Steffen Bollmann1,2,4, Simon Robinson1,5,6, Kieran O'Brien2,3, and Markus Barth1,2,4
1Centre for Advanced Imaging, University of Queensland, Brisbane, Australia, 2ARC Training Centre for Innovation in Biomedical Imaging Technology, University of Queensland, Brisbane, Australia, 3Siemens Healthcare Pty Ltd, Brisbane, Australia, 4School of Information Technology and Electrical Engineering, University of Queensland, Brisbane, Australia, 5High Field Magnetic Resonance Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 6Department of Neurology, Medical University of Graz, Graz, Austria

High-resolution Quantitative Susceptibility Mapping (QSM) has the potential to improve multiple sclerosis imaging and pre-surgical planning for deep brain stimulation. Using a conventional 3D-gradient echo sequence, imaging times for submillimeter scans can be as long as 8 to 15 minutes. In this work, we implemented a multi-shot 3D-EPI sequence combined with 2D CAIPIRINHA acceleration to achieve high-quality susceptibility maps, with no visible distortions, at 0.80 mm and 0.65 mm isotropic resolutions in 58 and 87 seconds, respectively. Multi-echo 3D-GRE sequences producing similar QSMs required up to a 9-fold increase in acquisition time.

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