Abstract #0787

Submillimeter, Sub-Minute Quantitative Susceptibility Mapping using a Multi-Shot 3D-EPI with 2D CAIPIRINHA Acceleration

Monique Tourell^1,2, Jin Jin^2,3, Ashley Stewart^1,2, Saskia Bollmann¹, Steffen Bollmann^1,2,4, Simon Robinson^1,5,6, Kieran O'Brien^2,3, and Markus Barth^1,2,4

¹Centre for Advanced Imaging, University of Queensland, Brisbane, Australia, ²ARC Training Centre for Innovation in Biomedical Imaging Technology, University of Queensland, Brisbane, Australia, ³Siemens Healthcare Pty Ltd, Brisbane, Australia, ⁴School of Information Technology and Electrical Engineering, University of Queensland, Brisbane, Australia, ⁵High Field Magnetic Resonance Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ⁶Department of Neurology, Medical University of Graz, Graz, Austria

High-resolution Quantitative Susceptibility Mapping (QSM) has the potential to improve multiple sclerosis imaging and pre-surgical planning for deep brain stimulation. Using a conventional 3D-gradient echo sequence, imaging times for submillimeter scans can be as long as 8 to 15 minutes. In this work, we implemented a multi-shot 3D-EPI sequence combined with 2D CAIPIRINHA acceleration to achieve high-quality susceptibility maps, with no visible distortions, at 0.80 mm and 0.65 mm isotropic resolutions in 58 and 87 seconds, respectively. Multi-echo 3D-GRE sequences producing similar QSMs required up to a 9-fold increase in acquisition time.

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