Abstract #0901

Rapid simultaneous T1 and T2 quantification (RAS-Q T1T2) of the myocardium using transient bSSFP with variable flip angles

Céline Marquet^1,2,3, Jihye Jang^1,2,4, Andrew J. Powell^1,2, and Mehdi H. Moghari^1,2

¹Department of Pediatrics, Harvard Medical School, Boston, MA, United States, ²Department of Cardiology, Boston Children's Hospital, Boston, MA, United States, ³Department of Informatics, Technical University Munich, Munich, Germany, ⁴Philips Healthcare, Boston, MA, United States

We developed a novel MRI pulse sequence RAS-Q T₁T₂ for the simultaneous quantification of T₁ and T₂ of the myocardium using transient bSSFP imaging with a variable flip angle scheme. RAS-Q T₁T₂ was systematically analyzed based on a numerical simulation, as well as phantom and patient studies. We show that RAS-Q T₁T₂ yields accurate T₂ estimates for the myocardium with a trade-off in precision compared to state-of-the-art methods, reducing scan time to less than 4s. The estimated T₁ values reveal lower accuracy and precision than clinically established methods and need further improvements.

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