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Abstract #0901

Rapid simultaneous T1 and T2 quantification (RAS-Q T1T2) of the myocardium using transient bSSFP with variable flip angles

CĂ©line Marquet1,2,3, Jihye Jang1,2,4, Andrew J. Powell1,2, and Mehdi H. Moghari1,2
1Department of Pediatrics, Harvard Medical School, Boston, MA, United States, 2Department of Cardiology, Boston Children's Hospital, Boston, MA, United States, 3Department of Informatics, Technical University Munich, Munich, Germany, 4Philips Healthcare, Boston, MA, United States

We developed a novel MRI pulse sequence RAS-Q T1T2 for the simultaneous quantification of T1 and T2 of the myocardium using transient bSSFP imaging with a variable flip angle scheme. RAS-Q T1T2 was systematically analyzed based on a numerical simulation, as well as phantom and patient studies. We show that RAS-Q T1T2 yields accurate T2 estimates for the myocardium with a trade-off in precision compared to state-of-the-art methods, reducing scan time to less than 4s. The estimated T1 values reveal lower accuracy and precision than clinically established methods and need further improvements.

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