Abstract #0902

Susceptibility artifact-insensitive ultrafast 3D gradient-echo imaging by combination of head-tilting and ERASE acquisition

Jaeyong Yu^1,2, Seulki Yoo^1,2, Jae-Kyun Ryu³, Seung-Kyun Lee^1,2,4, and Jang-Yeon Park^1,2,3

¹Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of, ²Department of Intelligent Precision Healthcare Convergence, Sungkyunkwan University, Suwon, Korea, Republic of, ³Biomedical Institute for Convergence at SKKU, Sungkyunkwan University, Suwon, Korea, Republic of, ⁴Center for Neuroscience Imaging Research, Institute for Basic Science (IBS), Suwon, Korea, Republic of

Equal-TE Rapid Acquisition with Sequential Excitation (ERASE) is a 3D ultrafast gradient-echo-based Spatiotemporal Encoding (SPEN) imaging technique with a constant TE and high tolerance to main magnetic field () inhomogeneity. However, misregistration of spin isochromat can occur due to large magnetic susceptibility-induced gradients in the prefrontal brain region. Here, we propose that shim improvement by chin-up head tilting can effectively mitigate misregistration in ERASE to realize fast prefrontal brain imaging with much higher image quality than conventional EPI.

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