MRI is a promising tool for the non-invasive study of animal model, but continues to face technical challenges. In this work, a Multitasking T1-T2 mapping technique was proposed for mouse abdominal imaging on 3T, which achieved 3D coverage, motion-resolved acquisition, and simultaneous T1 T2 mapping within 10 minutes. The study was performed on a murine model with liver metastasis of colorectal cancer. Data at multiple time points after tumor injection were acquired with different contrast agent, Eovist and ProCA.collagen1. The results demonstrated that 10-min Multitasking technique produced improved images with clear tumor delineation compared to conventional MRI series (50 minutes).