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Abstract #1008

Assessment of Shear Strain in Intervertebral Discs In Vivo with Magnetic Resonance Elastography

Yuan Le1, Jun Chen1, Phillip J. Rossman1, Ziying Yin1, Kevin J. Glaser1, Joshua D. Trzasko1, Yi Sui1, Stephan Kannengiesser2, Bradley D. Bolster, Jr.3, Joel P. Felmlee1, and Richard L. Ehman1
1Radiology, Mayo Clinic, Rochester, MN, United States, 2Siemens Healthcare GmbH, Erlangen, Germany, 3Siemens Medical Solutions USA, Inc., Salt Lake City, UT, United States

This study is to test the feasibility of visualizing waves propagating in the spine and measuring the strain in the intervertebral discs (IVDs) in vivo with Magnetic Resonance Elastography (MRE). Our results show that waves can be visualized, and that IVD shear strain can be quantitatively assessed. Degeneration of the IVD is thought to decrease disc shear stiffness. Preliminary results in a series of volunteers demonstrated increasing IVD shear strain with age, consistent with the known gradual degradation of IVD function with age.

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