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Abstract #1024

Deep Learning Automation for Human Brain Masking of Multi-Band MR Elastography

Aaron Thomas Anderson1,2, Siddharth Muralidaran3, Alexander M Cerjanic1,4, Bradley P Sutton1,4, Mark A Anastasio1,4, and Frank J Brooks1,4
1Beckman Institute for Advanced Science & Technology, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 2Stephens Family Clinical Research Institute, Carle Foundation Hospital, Urbana, IL, United States, 3Electrical & Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 4Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States

The processing steps involved in MR elastography include custom imaging sequences, image reconstruction, and material property estimation, but the most person-hours are spent on manual image masking. Manual corrections are needed because automated brain segmentation often fails near temporal lobe artifacts, which are unique for each subject. A deep learning method, specifically, a U-net architecture, is trained to map input MRE-image intensity data to corresponding manually corrected masks (N=44) with the goal of automating the masking of future MRE brain datasets. We observed the U-net-based masking maintained data quality (OSS-SNR) for all subjects.

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