Abstract #1050

Assessment of R1 Relaxometry Changes Induced via Repeated Videogame Training as a Measure of Neuroplasticity in College-aged Brains

Austin Bazydlo¹, Steven Kecskemeti², Aaron Cochrane³, Thomas Gorman⁴, Bas Rokers⁵, Douglas Dean^1,6, C. Shawn Green³, and Andrew Alexander^1,2,7

¹Medical Physics, UW-Madison, Madison, WI, United States, ²Waisman Center for Brain Imaging, UW-Madison, Madison, WI, United States, ³Psychology, UW-Madison, Madison, WI, United States, ⁴Psychology, Indiana University-Bloomington, Bloomington, IN, United States, ⁵Psychology, NYU-Abu Dhabi, Abu Dhabi, United Arab Emirates, ⁶Pediatrics, UW-Madison, Madison, WI, United States, ⁷Psychiatry, UW-Madison, Madison, WI, United States

Two video games, Need for Speed and Guitar Hero, were used as training tasks for two groups of college-aged, typically developing participants over 4 weeks and 10 total hours of training. Imaging was acquired before and after the first training session and upon completion of the last training session. The robust MPnRAGE sequence, which produces hundreds of T1 contrasts, was used to generate quantitative R1 maps. Longitudinal changes of R1 were observed in several parietal and temporal lobe areas, which may indicate a neuroplastic response due to video game training.

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