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Abstract #1063

Parahippocampal gyrus neuroanatomical and functional connectivity alterations in mTBI at the acute stage:a VBM and rsfMRI study

wenjing huang1, jing zhang2, wanjun hu2, guangyao liu2, yanli jiang2, and shaoyu wang3
1Second Clinical School, Lanzhou University, Lanzhou, China, 2Lanzhou University Second Hospital, Lanzhou, China, 3Siemens Healthineers, Shanghai, China

mTBI is not a static event, but a progressive injury. The neuroanatomical and functional alterations of mild traumatic brain injury (mTBI) at the acute stage can be an initial step of damages leading to cognitive and emotional deficit which can be developed in future in long-term period of injury. We analyzed early alterations in the gray matter volume (GMV) and functional connectivity (FC) alterations of mTBI patients within 7 days after injury, and found that early disruptions in left parahippocampal gyrus may appear in mTBI, which might be potentially related to the cognitive and emotional impairments.

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