mTBI is not a static event, but a progressive injury. The neuroanatomical and functional alterations of mild traumatic brain injury (mTBI) at the acute stage can be an initial step of damages leading to cognitive and emotional deficit which can be developed in future in long-term period of injury. We analyzed early alterations in the gray matter volume (GMV) and functional connectivity (FC) alterations of mTBI patients within 7 days after injury, and found that early disruptions in left parahippocampal gyrus may appear in mTBI, which might be potentially related to the cognitive and emotional impairments.
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