Abstract #1062

Central vein sign occurrence on FLAIR* in neuropsychiatric systemic lupus erythematosus patients

Francesca Inglese¹, Kenneth Hergaarden¹, Pierre-Louis Bazin², Gerda M. Steup-Beekman³, Tom J.W. Huizinga³, Jeroen de Bresser¹, and Itamar Ronen¹

¹Department of radiology, Leiden University Medical Center, Leiden, Netherlands, ²Faculty of Social and Behavioural Sciences, University of Amsterdam, Amsterdam, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

The central vein sign (CVS) is an imaging biomarker useful in multiple sclerosis (MS) diagnosis and to differentiate MS from other autoimmune diseases with inflammatory lesions, such as systemic lupus erythematosus with neuropsychiatric events (NP). The prevalence of CVS in SLE patients experiencing NP is unknown. We examined 16 NPSLE patients for presence of CVS using FLAIR* images, generated from FLAIR images acquired at 3T and T2*-weighted images acquired at 7T. Out of 491 white matter lesions, we found 4 confirmed and 1 suspected CVS lesions. Our data suggests that CVS may be present in random occurrence in NPSLE.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.