Abstract #1061

Radio-chemotherapy induced toxic leukoencephalopathy: ultra-high field MR findings

Laura Biagi^1,2, Rosa Pasquariello¹, Raffaello Canapicchi ¹, Chiara Ticci³, Claudia Dosi³, Graziella Donatelli^2,4, Mauro Costagli^1,2, Mirco Cosottini^2,4,5, Roberta Battini^3,6, Michela Tosetti^1,2, and Network IDEA⁷

¹Laboratory of Medical Physics and Magnetic Resonance, IRCCS Fondazione Stella Maris, Pisa, Italy, ²Imago7 Research Foundation, Pisa, Italy, ³Department of Developmental Neuroscience, IRCCS Fondazione Stella Maris, Pisa, Italy, ⁴Neuroradiology Unit, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy, ⁵Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy, ⁶Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy, ⁷Italian DEvelopmental Age Health Network (IDEA Network), Rome, Italy

The affirmation of the role of UHF MRI in the clinical setting requires the demonstration of its diagnostic and prognostic power, especially in the context of fields not yet sufficiently explored, such as diseases of pediatric age. This study presents a single case of radio-chemotherapy induced leukoencephalopathy in which UHF-MRI demonstrated its added value compared to traditional MR imaging in the characterization of lesions and in the detailed delineation of their localization.

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