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Abstract #1061

 Radio-chemotherapy induced toxic leukoencephalopathy: ultra-high field MR findings

Laura Biagi1,2, Rosa Pasquariello1, Raffaello Canapicchi 1, Chiara Ticci3, Claudia Dosi3, Graziella Donatelli2,4, Mauro Costagli1,2, Mirco Cosottini2,4,5, Roberta Battini3,6, Michela Tosetti1,2, and Network IDEA7
1Laboratory of Medical Physics and Magnetic Resonance, IRCCS Fondazione Stella Maris, Pisa, Italy, 2Imago7 Research Foundation, Pisa, Italy, 3Department of Developmental Neuroscience, IRCCS Fondazione Stella Maris, Pisa, Italy, 4Neuroradiology Unit, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy, 5Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy, 6Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy, 7Italian DEvelopmental Age Health Network (IDEA Network), Rome, Italy

The affirmation of the role of UHF MRI in the clinical setting requires the demonstration of its diagnostic and prognostic power, especially in the context of fields not yet sufficiently explored, such as diseases of pediatric age. This study presents a single case of radio-chemotherapy induced leukoencephalopathy in which UHF-MRI demonstrated its added value compared to traditional MR imaging in the characterization of lesions and in the detailed delineation of their localization.

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