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Abstract #1077

Investigating Relationships Between Multi-Scale Perfusion and Myelin Integrity in Patients with Relapsing-Remitting MS

Nicholas J Sisco1, Aimee Borazanci1, Richard Dortch1, and Ashley M Stokes1
1Neuroimaging Research, Barrow Neuroimaging Innovation Center, Phoenix, AZ, United States

The objective of this study is to develop magnetic resonance imaging (MRI) biomarkers that can probe complementary vascular function and myelin content. The development of biomarker assays to quantitatively probe both perfusion and myelin content is critical to assessing acute inflammatory activity and regenerative potential. We anticipate that this biomarker will give insight into the underlying pathophysiology of reversible and irreversible myelin damage.

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