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Abstract #1135

Feasibility of respiratory self-gated free breathing supine breast DCE-MRI using data-driven model consistency condition reconstruction

Ping N Wang1, Julia V Velikina2, Alexey A Samsonov2, Lloyd Estkowski3, Ty A Cashen3, Frederick Felcz2, Roberta M Strigel1,2,4, Frank R Korosec1,2, and James H Holmes2
1Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, 2Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States, 3Global MR Applications & Workflow, GE Healthcare, Madison, WI, United States, 4Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, United States

Advanced acquisition and reconstruction methods have been proposed to improve spatial and temporal resolution for prone breast DCE. However, limited work has been performed in the supine setting, which is used in most downstream clinical services including surgery and biopsy. In this work, we propose a radial acquisition combined with self-gating and MOCCO reconstruction. We assess performance of these methods using a simulated breast phantom with respiratory motion and contrast kinetics allowing evaluation of reconstruction accuracy against the assigned ground truth. Evaluation of both spatial and temporal quality was also performed in a first in-vivo patient volunteer.

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