We assessed the distribution of saturated fatty acid (SFA) in the adipose tissue around malignant tumors and the whole breast of patients with benign and malignant lesions. Bilateral gradient echo spectroscopic imaging sequence was acquired simultaneously. A voxel-wise analysis in the frequency domain was then applied to measure the SFA in each breast's adipose tissues and peri-tumoral region. Our results showed that the SFA was significantly higher around the malignant tumor than on the contralateral side, while no significant changes were observed with benign lesions. The results indicate that the SFA may be closely associated with the malignancy of lesions.
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