Abstract #1140

Combination of IVIM with DCE-MRI in diagnosis and prognostic evaluation of breast cancer

Yurong Zheng¹, Rui Wang¹, Li Li¹, Haoyuan Li¹, Pengfei Wang¹, Tiejun Gan¹, Jing Zhang¹, and Kai Ai²

¹Department of Magnetic Resonance, LanZhou University Second Hospital, Lanzhou, China, ²Philips Healthcare, Xi’an, China

Intravoxel incoherent motion (IVIM) combined with Dynamic Contrast Enhanced MRI (DCE-MRI) are meaningful MRI techniques applied to breast cancer. This study used DCE-derived parameters (voiume translocation constant, K^trans and rate constant, K_ep) and IVIM-derived parameters (diffusion coefficient, D and perfusion fraction, f) to perform correlation analysis with prognosis of breast cancer indexes (ER, PR, her-2, Ki-67). The preliminary results showed that there were correlations between K^trans, K_ep, D and prognostic factors of breast cancer. Our research may provide more important clinical evidence for the treatment and prognosis of breast cancer.

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