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Abstract #1144

B-value derivation for diffusion-weighted Double-Echo Steady-State (dwDESS) sequences

Ulrich Katscher1, Jakob Meineke1, Shuo Zhang2, and Jochen Keupp1
1Philips Research Europe, Hamburg, Germany, 2Philips Healthcare, Hamburg, Germany

To quantify diffusion weighting and to calculate the diagnostically valuable “Apparent Diffusion Coefficient” (ADC) in MR-based “Diffusion-Weighted Imaging” (DWI), a standardized b-value is typically used. To avoid typical shortcomings of standard DWI, diffusion-weighted double-echo-steady-state (dwDESS) sequences were proposed, which don’t show geometrical distortions. Balanced bipolar dwDESS, in particular, provides high SNR and is robust against motion. However, a proper definition of the b-value equivalent to standard DWI is not yet well addressed. This study investigated an estimation for effective b-values in dwDESS based on approximation of the underlying signal model, which was verified in phantom and human measurements.

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