Meeting Banner
Abstract #1193

Linear combination SSFP for multi-site chemical shift imaging: Applications to Deuterium Metabolic Imaging

Dana C. Peters1, Stefan Markovic2, Qingjia Bao2, Dina Preise2, Keren Sasson2, Lilach Agemy2, Avigdor Scherz2, and Lucio Frydman2
1Radiology and Biomed Eng., Yale University, New Haven, CT, United States, 2Weizmann Institute of Science, Rehovot, Israel

Deuterium metabolic imaging (DMI) is a new method to map abnormal metabolism of tumors. bSSFP might provide high SNR for DMI, due to the high T2/T1 ratios of the injected deuterated glucose, and the lactate, which arises from abnormal metabolism. We developed a linear-combination balanced SSFP method for spectrally resolving glucose, lactate and water, using predicted signal evolutions for different bSSFP phase-cyclings. Our method was able to generate images of the individual compounds in phantoms and in vivo.

This abstract and the presentation materials are available to members only; a login is required.

Join Here