Abstract #1259

Relaxation Anisotropy in Biological Tissues

Nina Elina Hänninen^1,2, Mikko Johannes Nissi^1,2, Matti Hanni^1,3,4, Olli Gröhn⁵, Miika Tapio Nieminen^1,3,4, and Timo Liimatainen^1,4

¹Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland, ²Department of Applied Physics, University of Eastern Finland, Kuopio, Finland, ³Medical Research Center, University of Oulu and Oulu University Hospital, Oulu, Finland, ⁴Department of Diagnostic Radiology, Oulu University Hospital, Oulu, Finland, ⁵A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland

Relaxation times of tissues can depend on tissue orientation with respect to main magnetic field. However, these effects are still unknown in many biological tissues. Relaxation anisotropy provides a base to develop novel quantitative MRI contrasts and unwrap the theory behind different relaxation mechanisms. We investigated relaxation anisotropy of conventional and rotating frame relaxation parameters in brain, spinal cord, tendon, cartilage, kidney and cardiac muscle tissue. The findings show that relaxation anisotropy varies between relaxation parameters and between different tissue types.

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