Abstract #1291

3D Quantitative MRI of the Brain: Effects of B1 Inhomogeneity in 3D-QALAS

Anders Tisell^1,2, Peter Lundberg^1,2, Marcel Jan Bertus Warntjes¹, and Frederik Testud³

¹CMIV, Linköping University, Linköping, Sweden, ²Medical Radiation Physics, Linköping University, Linköping, Sweden, ³Siemens Healthcare AB, Malmö, Sweden

We have implemented the 3D QALAS sequence for a 3 T MR-scanner and validated the accuracy and evaluated the effect of B1+ inhomogeneities on the resulting R1 and R2 estimations. When using a small flip angle of 4° the determined R1 and R2 maps showed a high accuracy; however, for 10° there was a significant bias and dependence on B1+ inhomogeneities.

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