Meeting Banner
Abstract #1306

Carbogen-based Cerebrovascular Reserve Using BOLD-based fMRI of Human Brain : tissue, territorial and cortical specificity

Tzu-chen Yeh1,2, Chou-ming Cheng3, and Chi-che Chou3
1Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, 2Institue of Brain Science, National Yang-Ming University, Taipei, Taiwan, 3Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan

Carbogen-based cerebrovascular reserve (CO2-CVR), derived from 90 normal subjects, was constructed for data-based approaches or analysis. Tissue, territorial and cortical specificities of CO2-CVR were evaluated by regions of interest (ROI) approaches. Global ratio of GM/WM CO2-CVR was about 1.57. Territorial and cortical specificities of CO2-CVR demonstrated (1) limited CO2-CVR in territories of posterior circulation which supported the pathophysiology of posterior reversible encephalopathy syndrome and (2) vital function in distal territories of anterior cerebral artery as verified by cortical parcellation with the highest of CO2-CVR at ventral portion of Brodmann area 23 (co-localized with posterior cingulate cortices of default mode network).

This abstract and the presentation materials are available to members only; a login is required.

Join Here