Abstract #1330

Evaluation of Saturation Effects in Simultaneous Multi-Contrast (SMC) Imaging

Nora-Josefin Breutigam¹, Daniel Christopher Hoinkiss¹, Mareike Alicja Buck ^1,2, Klaus Eickel^1,2, Matthias Günther^1,2, and David Porter³

¹Imaging Physics, Fraunhofer MEVIS, Bremen, Germany, ²Faculty 01 (Physics/Electrical Engineering), University Bremen, Bremen, Germany, ³Imaging Centre of Excellence (ICE), University of Glasgow, Glasgow, Scotland

Simultaneous multi-contrast imaging (SMC) can be used to combine acquisition of diffusion-weighted (DW) and T₂*-weighted (T₂*W) images into a single scan. Compared to conventional single-contrast imaging, SMC reduces the total scan time and improves image registration. However, saturation effects can reduce SNR and alter contrast. In this study, these effects are investigated in simulations, in phantoms, and in vivo. By using the results of this study to control saturation effects in SMC, the method enables rapid acquisition of distortion-matched, high-quality, well-registered DW and T₂*W imaging, which could support rapid diagnosis and treatment of acute stroke.

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