In this study, we propose a more robust PITA-MDD method with automatic brain ROI selection and adaptive thresholding for the motion threshold (termed APITA-MDD). Automatic brain ROI is initially identified by Otsu’s method and then improved by erosion and dilation. Haralick’s Homogeneity Index (HHI) of each slice is converted to a deviation score independent of image SNR and ROI size for motion detection. APITA-MDD was tested on brain dMRI data acquired with head motion and leg crossing motion and correctly detected motion slices missed by PITA-MDD due to insufficient coverage at edge slices and single thresholding.
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