We proposed a new end-to-end motion correction method based on conditional generative adversarial network (GAN) and minimum entropy of MRI images for Fast Spin Echo(FSE) sequence. The network contains an encoder-decoder generator to generate the motion-corrected images and a PatchGAN discriminator to classify an image as either real (motion-free) or fake(motion-corrected). Moreover, the image's entropy is set as one loss item in the cGAN's loss as the entropy increases monotonically with the motion amplitude, indicating that entropy is a good criterion for motion. The results show that the proposed method can effectively reduce the artifacts and obtain high-quality motion-corrected images from the motion-affected images in both pre-clinical and clinical datasets.
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