Patient motion continues to be a major problem in MRI. We propose and validate a novel deep learning approach for the correction of large movements in brain MRI. Training pairs were generated using in-house MRI data of high quality, and simulated images with artifacts based on real head movements. The images predicted by the proposed DL method from motion-corrupted data have improved image quality compared with the original corrupted images in terms of a quantitative metric and visual assessment by experienced readers.
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