Abstract #1371

Prospective motion-corrected three-dimensional multiparametric mapping of the brain

Shohei Fujita^1,2, Naoyuki Takei³, Akifumi Hagiwara¹, Issei Fukunaga¹, Dan Rettmann⁴, Suchandrima Banerjee⁵, Ken-Pin Hwang⁶, Shiori Amemiya², Koji Kamagata¹, Osamu Abe², and Shigeki Aoki¹

¹Department of Radiology, Juntendo University, Tokyo, Japan, ²Department of Radiology, The University of Tokyo, Tokyo, Japan, ³MR Applications and Workflow, GE Healthcare, Tokyo, Japan, ⁴MR Applications and Workflow, GE Healthcare, Rochester, MN, United States, ⁵MR Applications and Workflow, GE Healthcare, Menlo Park, CA, United States, ⁶Department of Radiology, MD Anderson Cancer Center, Houston, TX, United States

A rigid real-time prospective motion-corrected multiparametric mapping technique was developed by inserting orthogonal spiral navigators into wait times of a multiparametric imaging technique, 3D-QALAS. The effects of motion correction on the quantitative estimates of a standardized phantom and in volunteers with various head motions were evaluated. Our results demonstrated that the proposed technique did not affect the accuracy of T1 and T2 quantification in vitro, and improved the repeatability and accuracy of T1 and T2 quantification with head motions during scans compared with those without motion correction. The proposed technique may provide robust three-dimensional multiparametric whole-brain mapping for head motions.

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