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Abstract #1371

Prospective motion-corrected three-dimensional multiparametric mapping of the brain

Shohei Fujita1,2, Naoyuki Takei3, Akifumi Hagiwara1, Issei Fukunaga1, Dan Rettmann4, Suchandrima Banerjee5, Ken-Pin Hwang6, Shiori Amemiya2, Koji Kamagata1, Osamu Abe2, and Shigeki Aoki1
1Department of Radiology, Juntendo University, Tokyo, Japan, 2Department of Radiology, The University of Tokyo, Tokyo, Japan, 3MR Applications and Workflow, GE Healthcare, Tokyo, Japan, 4MR Applications and Workflow, GE Healthcare, Rochester, MN, United States, 5MR Applications and Workflow, GE Healthcare, Menlo Park, CA, United States, 6Department of Radiology, MD Anderson Cancer Center, Houston, TX, United States

A rigid real-time prospective motion-corrected multiparametric mapping technique was developed by inserting orthogonal spiral navigators into wait times of a multiparametric imaging technique, 3D-QALAS. The effects of motion correction on the quantitative estimates of a standardized phantom and in volunteers with various head motions were evaluated. Our results demonstrated that the proposed technique did not affect the accuracy of T1 and T2 quantification in vitro, and improved the repeatability and accuracy of T1 and T2 quantification with head motions during scans compared with those without motion correction. The proposed technique may provide robust three-dimensional multiparametric whole-brain mapping for head motions.

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