This work aims at improving the robustness of diffusion-weighted imaging (DWI) against 3D rigid head motion based on simultaneous multi-slice (SMS), interleaved echo-planar imaging (EPI) and image navigators. The proposed method utilizes low-resolution navigators to estimate diffusion phases as well as shot-wise 3D rigid motion through SMS-to-volume registration; providing high temporal resolution motion correction capability. The shot parameters are included into a full-volume reconstruction of the image data per diffusion direction. The method achieves submillimeter registration errors and improved image quality. In conclusion, the presented method enables retrospective 3D rigid motion correction for interleaved SMS DWI.
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