Abstract #1416

Stabilization of bias field on 3D MPRAGE at 7T with dielectric pads and 3D-based B1+ scaling

Giske Opheim¹, Vincent O. Boer², Esben Thade Petersen^2,3, Martin Prener¹, Olaf B. Paulson^1,4, and Jan Ole Pedersen⁵

¹Neurobiology Research Unit, Dept. of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark, ²Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Hvidovre, Denmark, ³Section for Magnetic Resonance, DTU Health Tech, Technical University of Denmark, Kgs. Lyngby, Denmark, ⁴Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, ⁵Philips Healhtcare, Copenhagen, Denmark

7T MRI has several cases of demonstrated clinical yield, but is challenged by spatial B₁ inhomogeneity. Bias fields in structural images may be acceptable for visual and computational analysis, and can to some extent be accounted for by bias-field corrections. However, this is significantly complicated since the characteristics of the bias field often varies between patients. By analyzing stability of bias fields in 3D MPRAGE images, we compared two dielectric pad setups and the impact of 3D-based B₁⁺ scaling, i.e., optimization of the RF gain. We found increased stability by using large pads and 3D-based B₁⁺ scaling in combination.

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