Abstract #1417

The impact of B1+ on the optimisation of high-resolution ASL acquisitions at 7T

Sriranga Kashyap¹, Roy A. M. Haast², Thomas F. Kirk³, An T. Vu^4,5, Denizhan Kurban¹, Ron Hellenbrand¹, Christopher J. Wiggins⁶, Alard Roebroeck¹, Ali R. Khan², David A. Feinberg^1,7,8, Benedikt A. Poser¹, and Dimo Ivanov¹

¹Department of Cognitive Neuroscience, Maastricht University, Maastricht, Netherlands, ²Centre for Functional and Metabolic Mapping, Western University, London, ON, Canada, ³University of Oxford, Oxford, United Kingdom, ⁴University of California, San Francisco, CA, United States, ⁵San Francisco Veteran Affairs Health Care System, San Francisco, CA, United States, ⁶Scannexus B.V., Maastricht, Netherlands, ⁷Advanced MRI Technologies, Sebastopol, CA, United States, ⁸Helen Wills Neuroscience Institute, University of California, Berkeley, CA, United States

In this 7T study, we examined potential causes of apparent absence of perfusion in the right inferior temporal lobe, by (i) assessing the B₁⁺ distributions on two 1Tx/32Rx head-coils to rule out a hardware source, and (ii) optimising the spatial positioning of dielectric pads to achieve a more symmetric B₁⁺ field. We observed that using an optimised dielectric pad positioning allows for a near whole-brain symmetric B₁⁺, thereby, ensuring the adiabatic condition for the inversion pulse is fulfilled, resulting in the robust measurement of perfusion in the right temporal lobes.

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