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Abstract #1417

The impact of B1+ on the optimisation of high-resolution ASL acquisitions at 7T

Sriranga Kashyap1, Roy A. M. Haast2, Thomas F. Kirk3, An T. Vu4,5, Denizhan Kurban1, Ron Hellenbrand1, Christopher J. Wiggins6, Alard Roebroeck1, Ali R. Khan2, David A. Feinberg1,7,8, Benedikt A. Poser1, and Dimo Ivanov1
1Department of Cognitive Neuroscience, Maastricht University, Maastricht, Netherlands, 2Centre for Functional and Metabolic Mapping, Western University, London, ON, Canada, 3University of Oxford, Oxford, United Kingdom, 4University of California, San Francisco, CA, United States, 5San Francisco Veteran Affairs Health Care System, San Francisco, CA, United States, 6Scannexus B.V., Maastricht, Netherlands, 7Advanced MRI Technologies, Sebastopol, CA, United States, 8Helen Wills Neuroscience Institute, University of California, Berkeley, CA, United States

In this 7T study, we examined potential causes of apparent absence of perfusion in the right inferior temporal lobe, by (i) assessing the B1+ distributions on two 1Tx/32Rx head-coils to rule out a hardware source, and (ii) optimising the spatial positioning of dielectric pads to achieve a more symmetric B1+ field. We observed that using an optimised dielectric pad positioning allows for a near whole-brain symmetric B1+, thereby, ensuring the adiabatic condition for the inversion pulse is fulfilled, resulting in the robust measurement of perfusion in the right temporal lobes.

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