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Abstract #1437

Feasibility of quantitative and volumetric enhancement measurement to assess tumor response in patients with breast cancer after early NACĀ 

Jie Ding1, Ruoshui Ha1, Weiwei Deng2, and Xiuzheng Yue3
1Medical Imaging Center, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, China, 2Philips Healthcare, Shanghai, China, 3Philips Healthcare, Beijing, China

The accuracy of early efficacy evaluation of neoadjuvant chemotherapy for breast cancer is important for clinicians to choose chemotherapy regimen.

75 lesions were assessed according to the ELV method in comparison with RECIST1.1 and TLV. In terms of predicting pathological response, the diagnostic accuracy of the three methods were analyzed and compared by receiver operating characteristic (ROC) curve analysis.

It is feasible for ELV in evaluating the responsiveness of breast cancer patients to early NAC on DCE-MRI images. Referring to the prediction the pathological response, ELV had the best diagnostic performance with highest sensitivity, accuracy, as well as AUC value.

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