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Abstract #1473

R1Ρ Dispersion imaging in human skeletal muscle at 3 Tesla

Fatemeh Adelnia1, Zhongliang Zu1,2, Feng Wang1,2, Kevin D Harkins3, and John C Gore1,2,3,4,5
1Vanderbilt University Institute of Imaging Science, Nashville, TN, United States, 2Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States, 3Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States, 4Department of Physics and Astronomy, Vanderbilt University, Nashville, TN, United States, 5Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, United States

R dispersion over a range of weak locking fields has the potential to reveal information on microvascular geometry and density such as microvascular spacing. This work presents in-vivo results supporting the application of R dispersion at low locking fields to the measurement of microvascular sizes and spacings in skeletal muscle. We present model fit parameters from measurements of R dispersion of human skeletal muscle that is close to ex-vivo data.

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