Abstract #1473

R1Ρ Dispersion imaging in human skeletal muscle at 3 Tesla

Fatemeh Adelnia¹, Zhongliang Zu^1,2, Feng Wang^1,2, Kevin D Harkins³, and John C Gore^1,2,3,4,5

¹Vanderbilt University Institute of Imaging Science, Nashville, TN, United States, ²Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States, ³Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States, ⁴Department of Physics and Astronomy, Vanderbilt University, Nashville, TN, United States, ⁵Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, United States

R_1ρ dispersion over a range of weak locking fields has the potential to reveal information on microvascular geometry and density such as microvascular spacing. This work presents in-vivo results supporting the application of R_1ρ dispersion at low locking fields to the measurement of microvascular sizes and spacings in skeletal muscle. We present model fit parameters from measurements of R_1ρ dispersion of human skeletal muscle that is close to ex-vivo data.

This abstract and the presentation materials are available to members only; a login is required.

Join Here